马光辉 研究员
  • 学历/学位: 研究生学历/博士学位
  • 研究方向: 尺寸均一、结构可控的生物颗粒制备及其在生物分离和制剂工程中的应用
  • 邮箱: ghma@ipe.ac.cn
  • 地址: 北京市海淀区中关村北二街1号
  • 邮编: 100190

简历介绍

马光辉研究员,博士生导师,生化工程国家重点实验室主任。国家杰出青年获得者(2001年),基金委创新群体首席,中国颗粒学会理事,中国化工学会生物化工专业委员会副主任委员,中国生物工程学会理事,国际期刊J Microencapsulation、IEC Res等期刊编委,Particuology、Eng Life Sci领域编辑。 研究方向为均一生物微球和微囊的制备及其在生化工程和医学工程中的应用,研究和开发用于生化分离、药物载体、免疫佐剂(疫苗递送系统)、细胞培养微载体等创新产品。在Nat. Mater., Nat. Biomed. Eng., Sci. Adv., Nat. Commun., JACS, Adv. Mater.等国际著名学术期刊上发表SCI论文400余篇,他引超过12000次,3篇论文先后获得Elsevier出版集团 “Highest Cited Original Research 2006 Awards”,“Top 50 Highly Cited Articles by Chinese Mainland Authors (2006-2010)”,“Top Cited Paper for 2010 and 2011”奖励。出版中英文专著11部,撰写学术书章节22篇,其中包括美国著名的化学工程师手册《Perry's Chemical Engineer's Handbook》(中国学者首次参加撰写)。中国发明专利授权88项,国际专利授权12项,专利技术和产品在国内外500多家单位得到应用。 主要获奖情况:国家技术发明二等奖(2009年),北京市科学技术一等奖(2005年)、中国化工学会科学技术奖基础研究成果奖一等奖(2020年),中国颗粒学会自然科学奖一等奖(2020年),中国科协全国优秀科技工作者(2016年),中国化工学会侯德榜化工科技创新奖(2014年)。

代表论著

1. Sha Peng#, Fengqiang Cao#, Yufei Xia*, Xiaodong Gao, Lianpan Dai, Jinghua Yan, Guanghui Ma*, Particulate alum via Pickering emulsion for an enhanced COVID-19 vaccine adjuvant. Advanced Materials 2020, 2004210. 
2. Yufei Xia#, Jie Wu#, Wei Wei, Yiqun Du, Tao Wan, Xiaowei Ma, Wenqi An, Aiying Guo, Chunyu Miao, Hua Yue, Shuoguo Li, Xuetao Cao, Zhiguo Su*, Guanghui Ma*, Exploiting the pliability and lateral mobility of Pickering emulsion for enhanced vaccination. Nature Materials 2018, 17 (2), 187-194. 
3. Yufei Xia#, Jie Wu#, Yiqun Du, Chunyu Miao, Zhiguo Su*, Guanghui Ma*, Bridging systemic immunity with gastrointestinal immune responses via oil-in-polymer capsules. Advanced Materials 2018, 30 (31), 201801067. 
4. Xiaoling Xie#, Yuxing Hu#, Tong Ye#, Yiran Chen, Lijuan Zhou, Feng Li, Xiaobo Xi, Shuang Wang, Yanjie He, Xiaoyong Gao, Wei Wei*, Guanghui Ma*, Yuhua Li*, Therapeutic vaccination against leukaemia via the sustained release of co-encapsulated anti-PD-1 and a leukaemia-associated antigen. Nature Biomedical Engineering 2020, s41551-020-00624-6. 
5. Xiaobo Xi#, Tong Ye#, Shuang Wang, Xiangming Na, Jianghua Wang, Shuang Qing, Xiaoyong Gao, Changlong Wang, Feng Li, Wei Wei*, Guanghui Ma*, Self-healing microcapsules synergetically modulate immunization microenvironments for potent cancer vaccination. Science Advances 2020, 6 (21), eaay7735. 
6. Nana Luo#, Jeffrey K. Weber#, Shuang Wang, Binquan Luan, Hua Yue, Xiaobo Xi, Jing Du, Zaixing Yang, Wei Wei*, Ruhong Zhou*, Guanghui Ma*, PEGylated graphene oxide elicits strong immunological responses despite surface passivation. Nature Communications 2017, 8, 14537. 
7. Yanlin Lv#, Feng Li#, Shuang Wang, Guihong Lu, Weier Bao, Yugang Wang, Zhiyuan Tian*, Wei Wei*, Guanghui Ma*, Near-infrared light-triggered platelet arsenal for combined photothermal-immunotherapy against cancer. Science Advances 2021, 7, eabd7614 
8. Chao Pan#, Jun Wu#, Shuang Qing#, Xiao Zhang, Lulu Zhang, Hua Yue, Ming Zeng, Bin Wang, Zheng Yuan, Yefeng Qiu, Huahu Ye, Dongshu Wang, Xiankai Liu, Peng Sun, Bo Liu, Erling Feng, Xiaoyong Gao, Li Zhu*, Wei Wei*, Guanghui Ma*, Hengliang Wang*, Biosynthesis of Self-Assembled Proteinaceous Nanoparticles for Vaccination. Advanced Materials 2020, 32 (42), 2002940. 
9. Shuang Qing, Chengliang Lyu, Li Zhu, Chao Pan, Shuang Wang, Feng Li, Jianghua Wang, Hua Yue, Xiaoyong Gao, Rongrong Jia, Wei Wei*, Guanghui Ma*, Biomineralized Bacterial Outer Membrane Vesicles Potentiate Safe and Efficient Tumor Microenvironment Reprogramming for Anticancer Therapy. Advanced Materials 2020, 32, 2002085. 
10. Yufei Xia#, Tiantian Song#, Yuning Hu, Guanghui Ma*, Synthetic Particles for Cancer Vaccines: Connecting the Inherent Supply Chain. Accounts of Chemical Research 2020, 53, 2068-2080.