魏炜，中国科学院过程工程研究所研究员，博士生导师，生物药制备与递送全国重点实验室主任。2004年本科毕业于北京大学医学部，同年保送进入中国科学院过程工程研究所硕博连读，2011年博士毕业后留所工作至今，先后破格晋升为副研究员和研究员。研究领域主要聚焦于仿生剂型工程，重点基于蛋白、细菌、细胞等天然对象，对载体进行仿生设计，并发展新的制备过程，借助仿生对象体内固有途径实现药物精准递送，应用于抗肿瘤、疫苗、组织修复等领域。

目前，共发表SCI论文151篇，他引9336次；其中，近十年以通讯作者在Nature、Nat Nanotechnol、Nat Biomed Eng、Sci Transl Med、Cell Host & Microbe等发表SCI论文85篇，包括20篇CNS正刊及子刊；授权4项国际发明专利和7项中国发明专利，3个剂型通过伦理批准并开展IIT研究；获亚洲杰出科研工作者和工程师奖、中国颗粒学会自然科学一等奖、中源协和生命医学创新突破奖等；主持了国家基金委杰出青年基金、国家重点研发计划、中国科学院战略性先导科技专项C类、中国科学院稳定支持基础研究领域青年团队计划等；担任中国化工学会生物化工专委会委员、中国疫苗行业协会疫苗基础研究专业委员会委员等。

1. Tong Ye#, Zhouguang Jiao#, Xin Li#, Zhanlong He, Yanyan Li, Fengmei Yang, Xin Zhao, Youchun Wang, Weijin Huang, Meng Qin, Yingmei Feng, Yefeng Qiu, Wenhui Yang, Lingfei Hu, Yaling Hu, Yu Zhai, Erqiang Wang, Di Yu, Shuang Wang, Hua Yue, Yishu Wang, Hengliang Wang*, Li Zhu*, Guanghui Ma*, Wei Wei*. Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization. Nature. 2023, 624: 630-638.

2. Peilin Guo#, Wenjing Wang#, Qian Xiang, Chao Pan, Yefeng Qiu, Tingting Li, Dongfang Wang, Jian Ouyang, Rongrong Jia, Min Shi, Yugang Wang, Junxia Li, Jiale Zou, Yuan Zhong, Jiawei Zhao, Diwei Zheng, Yimin Cui*, Guanghui Ma*, Wei Wei*. Engineered probiotic ameliorates ulcerative colitis by restoring gut microbiota and redox homeostasis, Cell Host & Microbe, 2024, 32: 1502-1518.

3. Han Bao#, Ying Tian#, Haixin Wang, Tong Ye, Shuang Wang, Jiawei Zhao, Yefeng Qiu, Jian Li, Chao Pan, Guanghui Ma*, Wei Wei*, Yong Tao*, Exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases. Nature Biomedical Engineering. 2024, 8: 1436-1452.

4. Xiaohong Chen#, Shuang Wang#, Yuxuan Chen#, Huhu Xin, Shuaishuai Zhang, Di Wu, Yanan Xue, Menglei Zha, Hongjun Li, Kai Li, Zhen Gu, Wei Wei*, Yuan Ping*. Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours. Nature Nanotechnology. 2023, 18: 933-944.

5. Xiaoming Hu#, Shuang Wang#, Shaotong Fu#, Meng Qin, Chengliang Lyu, Zhaowen Ding, Yan Wang, Yishu Wang, Dongshu Wang, Li Zhu, Tao Jiang, Jing Sun, Hui Ding, Jie Wu, Lingqian Chang, Yimin Cui, Xiaocong Pang, Youchun Wang, Weijin Huang, Peidong Yang, Limin Wang*, Guanghui Ma*, Wei Wei*. Intranasal mask for protecting the respiratory tract against viral aerosols. Nature Communications. 2023, 14: 8398.

6. Jiaqi Meng#, Yanlin Lv#, Weier Bao#, ZihuiMeng, Shuang Wang, Yuanbin Wu, Shuping Li, Zhouguang Jiao, Zhiyuan Tian*, Guanghui Ma*, Wei Wei*. Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation. Nature Communications. 2023, 14: 4505.

7. Changlong Wang#, Wei Zhang#, Yanjie He#, Zirui Gao, Liyuan Liu, Siyao Yu, Yuxing Hu, Shuang Wang, Chaochao Zhao, Hui Li, Jinan Shi, Wu Zhou, Feng Li, Hua Yue, Yuhua Li*, Wei Wei*, Guanghui Ma*, Ding Ma*. Ferritin-based targeted delivery of arsenic to diverse leukemia types confers strong anti-leukemia therapeutic effects. Nature Nanotechnology. 2021, 16: 1413-1423.

8. Shuang Wang, Feng Li, Tong Ye, Jianghua Wang, Chengliang Lyu, Shuang Qing, Zhaowen Ding, Xiaoyong Gao, Rongrong Jia, Di Yu, Jun Ren, Wei Wei*, Guanghui Ma*. Macrophage-tumor chimeric exosomes accumulate in both lymph node and tumor for activation of immune response and tumor microenvironment. Science Translational Medicine. 2021, 13: eabb6981.

9. Ying Tian#, Fan Zhang#, Yefeng Qiu, Shuang Wang, Feng Li, Jiawei Zhao, Chao Pan, Yong Tao*, Di Yu*, Wei Wei*. Reduction of choroidal neovascularization via cleavable VEGF antibodies conjugated to exosomes derived from regulatory T cells. Nature Biomedical Engineering. 2021, 5: 968-982.

10. Xiaoling Xie#, Yuxing Hu#, Tong Ye#, Yiran Chen, Lijuan Zhou, Feng Li, Xiaobo Xi, Shuang Wang, Yanjie He, Xiaoyong Gao, Wei Wei*, Guanghui Ma*, Yuhua Li*. Therapeutic vaccination against leukaemia via the sustained release of co-encapsulated anti-PD-1 and a leukaemia-associated antigen. Nature Biomedical Engineering. 2021, 5: 414-428.