韩业君 研究员
  • 学历/学位: 研究生学历/博士学位
  • 研究方向: 酶制剂和生物合成工程
  • 邮箱: yjhan@ipe.ac.cn
  • 地址: 北京市海淀区中关村北二街1号
  • 邮编: 100190
  • 课题组网站:

简历介绍

韩业君，研究员、博士生导师。2004年，获南京农业大学微生物学专业硕士学位。2008年, 获中国科学院过程工程研究所生物化工专业博士学位。2008年至2013年，先后在伊利诺伊大学-香槟分校和北卡州立大学，从事微生物和生物合成领域的博士后研究。2013年，进入中科院过程工程研究所、生化工程国家重点实验室工作。目前主要进行酶催化和生物合成工程方面的基础和应用研究，涉及合成生物学、酶制剂、微生物代谢工程、含碳气体的生物固定和转化等领域。迄今在生物工程领域学术期刊上发表论文50篇, 担任Applied and Environmental Microbiology、Energies等学术期刊编委。2017年，获第三届“闵恩泽能源化工奖”杰出贡献奖。

代表论著

1. Caihong Weng, Ruohao Tang, Xiaowei Peng, Yejun Han*. Co-conversion of lignocellulose-derived glucose, xylose, and aromatics to polyhydroxybutyrate by metabolically engineered Cupriavidus necator. Bioresource Technology, 2023(374): doi: 10.1016/j.biortech.2023.128762. 

2. Caihong Weng, Ruohao Tang, Xiaowei Peng, Yejun Han*. From methane to value-added bioproducts: microbial metabolism, enzymes, and metabolic engineering. Advances in Applied Microbiology, 2023(124): 119-146.

3. Haiqian Yang, Xiaojing Jia, Yejun Han*. Microbial redox coenzyme engineering and applications in biosynthesis. Trends in Microbiology. 2022, 30(4), https://doi.org/10.1016/j.tim.2022.01.012.

4. Ruohao Tang#, Xiaowei Peng#, Caihong Weng, Yejun Han*. The over-expression of phasin and regulator genes promoting the synthesis of polyhydroxybutyrate in Cupriavidus necator H16 under non-stress conditions. Applied and Environmental Microbiology. 2022, 88(2), https://doi.org/10.1128/AEM.01458-21.

5. Biao Geng, Xiaojing Jia, Xiaowei Peng, Yejun Han*. Biosynthesis of value-added bioproducts from hemicellulose of biomass through microbial metabolic engineering. Metabolic Engineering Communications. 2022(15), https://doi.org/10.1016/j.mec.2022.e00211.

6. Caihong Weng, Xiaowei Peng, Yejun Han*. Depolymerization and conversion of lignin to value-added bioproducts by microbial and enzymatic catalysis. Biotechnology for Biofuels and Bioproducts. 2021. 14:84, https://doi.org/10.1186/s13068-021-01934-w.

7. Ruohao Tang, Caihong Weng, Xiaowei Peng*, Yejun Han*. Metabolic engineering of Cupriavidus necator H16 for improved chemoautotrophic growth and PHB production under oxygen-limiting conditions. Metabolic Engineering. 2020. 61:11-23.

8. Hong Su, Ruohao Tang, Xiaowei Peng, Yejun Han*. Corrosion behavior and mechanism of carbon steel influenced by interior deposit microflora of an in-service pipeline. Bioelectrochemistry. 2020. https://doi.org/10.1016/j.bioelechem.2019.107406.

9. Xiaojing Jia, Yejun Han*. Simultaneous biosynthesis of (R)-acetoin and ethylene glycol from D-xylose through in vitro metabolic engineering. Metabolic Engineering Communications. 2018. https://doi.org/10.1016/j.mec.2018.e00074.

10. Xiaowei Peng, Yejun Han*. Sequential processing with fermentative Caldicellulosiruptor kronotskyensis and chemolithoautotrophic Cupriavidus necator for converting rice straw and CO2 to polyhydroxybutyrate. Biotechnology and Bioengineering. 2018. 10.1002/bit.26578.